Saffron Extract
Product Description
Imbalances in brain neurotransmitters such as serotonin, dopamine, and GABA contribute to symptoms of mood changes and anxiety.[1,2,3] Saffron Extract promotes serotonin and neurotransmitter balance in the brain, helping to reduce levels of anxiousness and stress response for a sense of calm.*
Supplementing with Saffron Extract supports healthy mood balance and positive outlook and provides antioxidant support for healthy inflammatory response and central (CNS) nervous system function. Adding this supplement to your daily regimen can support healthy brain function and healthy vitality in addition to helping support a healthy response to anxiousness for restful sleep. Saffron can even support a positive response to PMS symptoms.*
Vital Nutrients Saffron Extract comes in small, easy-to-take capsules using bioactive saffron components at clinically studied doses.[4,5]
It works by supporting the balance of serotonin metabolism in the microbiome, influencing tryptophan and serotonin responses in the brain, which also indirectly supports healthy dopamine and GABA expression, as well as modulation of the HPA axis, antioxidant support, and immune support.[4,6]
Packaging and label may vary.
References:
1. Pourhamzeh M. Cell Mol Neurobiol. 2022;42(6):1671-1692.
2. Grace A. Nat Rev Neurosci. 2016;17(8):524-532.
3. Conde KM. Metabolism. 2025;163:156099.
4. Lin S et al. Psychopharmacology. 2022;239:3657-3677.
5. Mena-Garcia A et al. Foods. 2023;12:1634.
6. Shafiee M. J Affect Disord. 2018;227:330-337.
Suggested Use
Take 2 capsules daily, one in the morning and one at night,
Or as directed by your healthcare professional.
Supplement Facts
2 capsules
| Nutrient | Amount Per Serving | % Daily Value |
|---|---|---|
| Saffron Extract (Crocus sativus, stigma, standardized to >2% safranal, >2% crocin, picrocrocin, >15% total mixed carotenoids) (SaffSerene™) | 30 mg | * |
Other Ingredients: Cellulose, Vegetarian Capsule (cellulose), Rice Bran Lipid, Silica.
*Daily Value not established
Whom is Saffron Extract for?
Saffron is a natural product solution for those wanting to improve and balance occasional changes in feelings of stress and anxiousness and improve calmness.
How quickly will I see results?
Responses will vary by individual, but you may see results in as quickly as a few hours to a few days. The level of saffron per serving meets the clinical efficacious levels supported in scientific studies.
Is Saffron Extract safe for kids?
Saffron is a naturally available spice from the crocus sativa flower. It has been used for centuries and is safe in food and small doses as a supplement for children. Please check with your healthcare professional to see if saffron can be appropriate for your child and what amount can be used.
Is Saffron Extract safe while pregnant or nursing?
Pregnant and lactating women should always consult with their healthcare professionals to determine the appropriate use of herbs and botanicals.
Is Saffron Extract safe to take with other medications?
Consult with a healthcare professional before starting use of saffron, especially if taking other medications, such as blood thinners, blood pressure medications, antidepressants or mood medications, sedatives, and/or diabetic medications. Contraindications for use are by those with conditions of bipolar disorder, low blood pressure, prior to surgeries, or blood disorders.
What makes Saffron Extract superior to other saffron supplements on the market?
The saffron used in Saffron Extract is harvested by hand in Iran and processed as a natural extract powder in Spain to standardize the two specific active phytonutrients in the plant, saffranal and crocin, along with carotenoids. Saffron is a highly bioavailable, safe, and effective naturally produced spice that has been used for general health support purposes for more than 1,000 years and is supported by clinical studies.